Pythonnet is a package that gives Python programmers an integration with the .NET Common Language Runtime (CLR).

Our ZOS-API is a .NET 4.8-based library. So the Pythonnet version should support .NET 4.8 to be used with ZOS-API.

We had some reports that pythonnet 3.0 didn’t work with ZOS-API. I also did a couple of tests last week and encountered issues. So the recommendation for now is not to use pythonnet 3.0 with ZOS-API.

I personally use pythonnet 2.5.2.